Alfonso married Isabella of Asturias, Princess of the Asturias on 18 Apr 1490 in Seville, Spain. Isabella (daughter of Ferdinand V "The Catholic" of Spain, 1st King of Spain and Isabella "The Catholic" of Castile, Queen of Castile) was born on 2 Oct 1470 in Duenas; died on 23 Aug 1498 in Saragosa; was buried in Sta. Isabel, Toledo. [Group Sheet] [Family Chart]